PIMSIREE02 email: fscicprsu@ku.ac.th or pimsiree.s@ku.ac.th
Education: B.S. (Materials Science and Engineering), Carnegie Mellon University, U.S.A.
Ph.D. (Materials Science and Engineering, University of Virginia, U.S.A
Research interests: 1) Biomaterials
2) Advanced Materials

Materials for Bone Repair: Composite of Hydroxyapatite and Biodegradable Polymer

Hydroxyapatite (HA) is an inorganic compound that has chemical composition similar to that of human bones. It is widely used in biomedical applications due to its excellent biocompatibility, bioactivity and osteoconductive properties. My interest is to fabricate and enhance bioactivity of hydroxyapatite to increase its ability to stimulate bone formation and antimicrobial property. One possible approach is by incorporating different cations and/or other substances such bone morphogenetic protein (BMP) to the hydroxyapatite.

The use of hydroxyapatite for heavy load bearing applications is, however, still limited.  This is because HA has low tensile strength, low flexibility and low fracture toughness, which do not match those of the bone tissue being replaced. These mechanical properties are expected to improve by compositing HA with other materials such as polymers. My interest is in biodegradable polymers as they can gradually resolve and later on can be totally replaced by the new bone.  Therefore, there will be no need for additional surgery to remove an implant.

Selected Publications

1. S.R. Taylor, F. Contu, R. Santhanam and P. Suwanna, “The use of cationic fluoroprobes to characterize ionic pathways in organic coatings”, Progress in organic coatings, 2012, 73, pp. 169-172.

2. P. Moongkhamklang , V.S. Deshpande and H.N.G. Wadley, “The compressive and shear response of titanium matrix composite lattice structures”, Acta Materialia, 2010, 58, pp. 2822-2835.

3. P. Moongkhamklang and H.N.G. Wadley, “Titanium alloy lattice structures with millimeter scale cell size”, Advanced Engineering Materials, 2010, 12, pp. 1111-1116.

4. P. Moongkhamklang, D.M. Elzey and H.N.G. Wadley, “Titanium matrix composite lattice structures, Composites Part A: Applied Science and Manufacturing, 2008, 39, pp. 176-187.

5. P. Moongkhamklang and S.R. Taylor, “The delineation of local water interaction with epoxy coating using fluorescence microscopy”, Progress in organic coatings, 2005, 54, pp. 205-210.research-Pimsiree